1. Which of the following compounds is the first member of the TCA cycle to be regenerated at the end of each cyclic turn?
- Citric acid
- Succinic acid
- Malic acid
- Oxaloacetic acid (OAA)
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Answer: (D) Oxaloacetic acid (OAA)
Oxaloacetic acid (OAA, a 4-carbon compound) condenses with acetyl CoA to form citric acid at the start of the cycle, and is regenerated at the end after the oxidation of malate by malate dehydrogenase.